from Capsule - Based Dry Powder Inhalers
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منابع مشابه
"Pierce and inhale" design in capsule based dry powder inhalers: Effect of capsule piercing and motion on aerodynamic performance of drugs.
In this work three capsule-based dry powder inhalers, available for generics product development, were compared. Two technologically different dry powder formulations were used in order to relate the capsule piercing position and motion in the device to their aerodynamic performance. A "pierce and inhale" design, in which the capsules pierced with RS01, HandiHaler or Turbospin devices were aero...
متن کاملImpact of capsule selection on formulation stability in dry powder inhalers (DPIs)
The delivery of inhalation-based formulations is achieved by devices that fall into three segments: nebulizers, metered dose inhalers (MDIs), and dry powder inhalers (DPIs).2 There is much discussion about which device is most appropriate, though that discussion is well beyond the scope of this article. It is of note however, that MDIs and DPIs have been shown to function equally well when pati...
متن کاملInhaled Therapeutics using Dry Powder Inhalers (DPI)
Dry powder inhalers (DPIs), opposed to the traditional pre-metered dose inhalers (MDIs), prove to be more advantageous in delivering the desired dosage of medication to the targeted site. Now, engineers are designing better DPIs and new carrier particles that have better characteristics for drug delivery.
متن کاملMetered-dose inhalers and dry powder inhalers in aerosol therapy.
Inhaled drug delivery is an important part of the armamentarium of clinicians caring for patients with pulmonary disease. An increasing variety of metered-dose inhalers and dry powder inhalers are becoming available. This has been driven by the development of new formulations and the impending ban on chlorofluorocarbon propellants. The result is a proliferation of devices, resulting in a confus...
متن کاملDelivery characteristics of a low-resistance dry-powder inhaler used to deliver the long-acting muscarinic antagonist glycopyrronium*
OBJECTIVES The long-acting muscarinic antagonist (LAMA) glycopyrronium (NVA237) has recently been approved as a once-daily treatment for COPD. The objectives of this study were to determine the dose delivery characteristics of glycopyrronium and compare them with those of the LAMA tiotropium, both delivered by their respective capsule-based dry-powder inhalers (DPIs). RESEARCH DESIGN AND METH...
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تاریخ انتشار 2018